Cancer Biomarker Market Competitive Landscape and Regional Analysis & Forecasts to 2025

10 Oct 2018 – Global Cancer Biomarker Market is anticipated to reach USD 33.7 billion by 2025. Biomarkers imply the molecules or substances found in tissues, blood, or the other body fluid; which states the abnormal and normal condition of the body. The cancer biomarkers tests are conducted to detect mutated or normal genes responsible for cancer.

The factors that propel the growth of the cancer biomarker industry include advancements in omics technologies, prevalence of cancer, growth in R&D funding from private bodies and government, rising healthcare spending, and increasing demand for personalized medicine in cancer treatments. On the other hand, there are factors that may hamper the growth of the market including reimbursement issues, need for immediate processing, and high cost of diagnosis. Cancer Biomarker Market is anticipated to grow at a significant CAGR of 14.3% in the upcoming period as the scope, product types, and its applications are increasing across the globe.

Cancer biomarker industry may be explored by type, application, biomolecule type, and geography. The market may be explored by type as Lung cancer, Prostate cancer, Breast cancer, Colorectal cancer, Liver cancer, Cervical cancer, Others. The “Breast Cancer” segment led the market in 2016 and is anticipated to maintain its dominance by 2025 owing to growing consciousness about initial testing and rising base of target populace.

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The key applications that could be explored in the Cancer Biomarker Market include Personalized medicine, Diagnostics, Drug Discovery and Development, and Others. The “Diagnostics” segment led the market in 2016 and is anticipated to maintain its dominance by 2025 due to growing development of biomarker-based oncology tests with high sensitivity and specificity.

The cancer biomarker industry could be explored based on Biomolecules type as Epigenetic Biomarkers, Proteomic Biomarkers, Genetic Biomarkers, Metabolic Biomarkers, and Others. The “Genetic biomarkers” segment led the market in 2016 and is anticipated to maintain its dominance by 2025 due to high-reliability rate, and extensive usage.

North America accounted for the major share of the cancer biomarker market size in 2016 and will continue to lead in the forecast period. The factors that could be ascribed to the growth include increasing demand for personalized medicine, growing government funding for development and discovery of biomarkers, growing use of biomarkers in Drug Discovery and growth by pharmaceutical industries in that country, and acceptance of innovative omics technologies for biomarker discovery.

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Some of the key players that fuel the growth of the cancer biomarker industry comprise F-Hoffmann-La Roche Ltd.; Abbott Laboratories; Thermo Fisher Scientific Inc.; QIAGEN; Affymetrix Inc.; Agilent Technologies; Illumina, Inc.; Merck & Co. Inc.; Sino Biological Inc.; Hologic, Inc.; Dickinson and Company, and Becton. The leading companies are taking up partnerships, mergers and acquisitions, and joint ventures in order to boost the inorganic growth of the industry.

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Live Cell Imaging Market Analysis, Competitive Strategies And Forecasts 2025

19 Sep 2018 – Global Live Cell Imaging Market is estimated to reach USD 9.0 billion by 2025 owing to the increasing popularity of kinetic research over fixed cellular analysis. Live cell imaging is the study of cells in real-time with the help of images obtained from microscopes and screening systems. Technology has enhanced the approach of scientists to examine proteins, internal cell structures molecular synergy and cellular processes. This allows them to observe cells and to understand the in-depth analysis instead of learning the images of fixed cells.

More information that is precise can be achieved with the help of live cell imaging that plays an important role in understanding cell dynamics in research fields like immunology, microbiology, neurology and others. Technological modernizations in live cell imaging are projected to fulfil the demands of different end-users. Technological improvements along with other factors are likely to boost the live cell imaging market in the forecast period at CAGR of 8.5%.

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The growing concern of cancer is one of the major factors for the rising demand for the live cell imaging technology. Moreover, governments worldwide are taking initiatives to fund the cell-based research which will contribute live cell imaging industry. Besides, live cell imaging can be used for a wide number of applications along with understanding of dynamics processes of cellular structures. Additionally, live cell imaging can also be used to study cell integrity, enzyme activity, protein trafficking exocytosis, localization of molecules and endocytosis among others. Likewise, the process can also be applied to observe the molecules in live animals.

The pharmaceuticals companies are also adopting the live cell imaging for high-quality screening. Conversely, the costly installation of live cell imaging is acting as a restraint for the live cell imaging industry. Dearth in technical proficiency also restrains the market growth. Moreover, with rising investments in training and developments programs is expected to affect comparatively less in the near future. Also, the live cell imaging techniques is gradually being used in the pharmaceutical companies to develop personalized medicine which is predicted to fuel the market.

Live cell imaging market is categorized on the basis of product type, technology, application and geography. On the basis of product type, the market is divided into Consumable, Equipment, and Software. Equipment is projected to hold larger share of live cell imaging industry in near future. The equipment segmented is further divided into microscopes, cell analyzers, standalone systems, and image-capturing instruments. Based on consumables, the market is divided into assay kits, media, reagents and others.

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In terms of technology, live cell imaging market is segmented into fluorescence in situ hybridization (FISH), fluorescence resonance energy transfer (FRET), fluorescence recovery after photobleaching (FRAP), high-content analysis (HCA), ratiometric imaging, total internal reflection fluorescence microscopy (TRIF), multiphoton excitation microscopy (MPE), and others. On the basis of application, is divided into Stem cells, Cell Biology and Drug Discovery.

Geographically, the market is segmented as North America, Europe, Asia Pacific, Latin America and Middle East & Africa. North America is predicted to hold larger share of the market followed by Asia Pacific and Europe. The prominent live cell imaging industry players comprise Becton, Carl Zeiss AG, Leica Microsystems, Molecular Devices, LCC, PerkinElmer, Inc., Nikon Corporation, GE Healthcare, Dickinson and Company, Thermo Fisher Scientific, Inc., Olympus Corporation, and Sigma-Aldrich Corporation.

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Protein Engineering Market Dynamics, Forecast, Analysis and Supply Demand 2025

19 Sep 2018 – Global Protein Engineering Market is anticipated to reach USD 3.09 billion by 2025. Protein engineering is a method to design novel proteins or enzymes with the intention to have functional properties. Protein engineering is primarily based on the use of recombinant DNA technology to alter the amino acid sequences in terms of affinity, solubility, activity, resistance, etc.

The factors that propel the growth of the Protein Engineering industry include increasing occurrence of lifestyle associated diseases, increasing consciousness regarding healthcare, increasing healthcare expenditure, and growing adoption of protein-based drugs. On the other hand, there are factors that may hamper the growth of the market including lack of skilled expertise, maintenance, and high price of tools as well as instruments utilized during protein engineering. Protein Engineering Market is anticipated to grow at a significant CAGR of 15.9% in the upcoming period as the scope, product types, and its applications are increasing across the globe.

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The market may be explored by product type, technology, protein type, end users, and geography. The market may be explored by product type as services and software, instruments, and reagents. The “Instruments” segment dominated the market in 2016 and is anticipated to maintain its dominance in the forecast period.

The key technologies that could be explored in the Protein Engineering industry include Irrational Protein Design, and Rational Protein Design. The “Rational Protein Design” segment dominated the market in 2016 and is anticipated to maintain its dominance by 2025 owing to highly accepted technology in the market in 2014. This huge share could be ascribed to its advantages over irrational protein design technology.

The Protein Engineering Market could be explored based on protein type as Insulin, Erythropoietin, Vaccines, Monoclonal Antibodies, Interferon, Growth hormones, Colony Stimulating factor, Coagulation Factor, Others (Follicle Stimulating Hormones, Enzyme Replacement, and Interleukins). The “Monoclonal Antibodies” segment dominated the market in 2016 and is anticipated to maintain its dominance by 2025 owing to increase in acceptance for several treatments such as autoimmune diseases, and cancer.

Protein Engineering industry could be analyzed by end user as contract research organizations, academic research institutes, and pharmaceutical & biotechnology companies. The “Pharmaceutical and Biotechnology Companies” segment dominated the market. The factors contributing to the dominant share include increase in R&D funds in the pharmaceutical segment, and technological advancements in protein engineering.

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North America is anticipated to hold the major share of the Protein Engineering Market. The factors that attribute to the dominant share include growing occurrence of diseases and rising adoption of protein-based drugs in the region. The North American market is followed by Europe. On the other hand, Asia Pacific is estimated to show high growth rates in the upcoming period in the global market. In the Asia Pacific region, countries such as China and India are expected to be the fastest-growing markets.

Some of the key players that fuel the growth of the Protein Engineering industry comprise Eli Lilly and Company, Thermo Fisher Scientific Inc., Merck KGaA, Bruker Corporation, PerkinElmer Inc., Agilent Technologies, Waters Corporation, Novo Nordisk A/S, Bio-Rad Laboratories Inc., Amgen Inc., and among others. The leading companies are taking up partnerships, mergers and acquisitions, and joint ventures in order to boost the inorganic growth of the industry.

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Glycomics/Glycobiology Market Trends, Analysis, Leading Players & Future Forecast by 2025

The global Glycomics/Glycobiology Market is expected to grow at a CAGR of 14.4% in the forthcoming period. Glycomics is a wide and emerging scientific field emphasizing on defining functional aspects of glycans in biological systems. The higher the complexity of glycome, which is defined as the range of glycans particularly in a cell or organism leads to multiple challenges that could be subjectively decoded.

The challenges are resolved with progress in mass spectrometry along with expansion of genetic and cell biology studies. On the contrary, determining a specific glycan and glycan-binding proteins by incorporating new technology of glycan microarrays guide the glycan function. Glycomics/glycobiology industry is driven by factors such as growing investments for R&D with a strong emphasis of pharmaceutical and biotechnology companies on innovative product development. Rise in development of new vaccines for genetic diseases comprising diabetes and influenza will add to the market growth in the forecast period. Rise in government funding for R&D activities and novel approach for drug production process are the other factors driving the market.

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Product segmentation for glycomics market includes enzymes, reagents, kits and instruments. Enzymes are further quad furcated into glycosyltransferases, neuraminidases, sialyl transferases and glycosidases. Enzyme segment accounts for a high market share due to wide applications for various drug recovery procedures. Application segment for glycomics/glycobiology industry includes drug discovery &development diagnostics.

Regional segmentation for glycomics/glycobiology market includes North America, Latin America, Europe, Asia-Pacific, Middle East and Africa. North America dominates the market due to high revenue share and presence of large pharmaceutical & biotechnology firms. Presence of developed healthcare infrastructure and availability of advanced products in these regions is likely to promote the market growth.

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Asia-Pacific’s glycobiology industry is estimated to grow at a higher CAGR in the forecast period due to booming healthcare infrastructure in emerging economies. Availability of large pool of patients and low cost of clinical trials and accessibility of skilled personnel have propelled the market growth in Asia-Pacific’s market. The key players in the glycomics/glycobiology market include Thermo Fisher Scientific Inc, Agilent Technologies, Bruker, Merck KGaA, Shimazdu Corp, New England Biolabs, Waters Corporation, and Takara Bio Inc.

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Aptamers Market Segments, Share and Growth Factor Analysis Research Report 2025

Global Aptamers Market is anticipated to reach USD 8.91 billion by 2025. Aptamers implies peptide or oligonucleotides molecules that bind to target protein, nucleic acid, lipid molecules with a high specificity. Rapidly generated Aptamers are applied for specific detection, characterization, and inhibition of proteins. They have several characteristics and could be used as pharmaceutical leads, detection reagents, small molecules, efficient proteomic stages with antibodies, and the other aptamers.

The factors that propel the growth of the aptamers industry include strong trend of R&D savings in pharmaceutical and biotechnology industries, technological advancements, patent expiration of systematic development of ligands by exponential improvement technology (SELEX), and the low price and high productivity of aptamers in binding to large molecules as related to antibodies. On the other hand, there are factors that may hamper the growth of the market including low awareness of technology, and low-income countries. Aptamers Market is anticipated to grow at a significant CAGR of 28.2% in the upcoming period as the scope, product types, and its applications are increasing across the globe.

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Aptamers industry may be explored by type, technology, application, end user, and geography. The market may be explored by type as XNA-Based Aptamers, and DNA-Based Aptamers, RNA-Based Aptamers. The “DNA-based Aptamers” segment led the market in 2016 and is anticipated to maintain its dominance by 2025; even though XNA-based aptamers will increase at the highest CAGR between 2015 and 2025 owing to increase in demand for nucleic acid-based diagnostic therapeutics and kits across the globe.

The key applications that could be explored in the aptamers market include Research and Development, Therapeutics Development, Diagnostics, and Other Applications. The “Diagnostics” segment led the market in 2016 and is anticipated to maintain its dominance by 2025 owing to introduction of novel diagnostic kits by major companies.

The aptamers industry could be explored based on end user as Contract Research Organizations, Biotechnology and Pharmaceutical Companies, Academic and Government Research Institutes, and Other End Users. The “Academic And Government Research Institutes” segment led the market in 2016 and is anticipated to maintain its dominance by 2025 followed by Biotechnology and Pharmaceutical Companies segment. The industry may be analyzed by technology as SELEX, and Other Technologies. The “Other Technologies” segment led the market in 2015 and is anticipated to maintain its dominance by 2025.

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North America accounted for the major share of the aptamers market size in 2016 and will continue to lead in the forecast period. The factors that could be attributed to the growth include increasing number of companies coupled with increasing R&D activities in this area, and continuous technological advancements in technologies, growing number of research laboratories and promising government initiatives.

Some of the key players that fuel the growth of the aptamers industry comprise Aptamer Group, Somalogic Inc., Aptamer Sciences Inc., Aptagen LLC, Noxxon Pharma, Base Pair Biotechnologies Inc., Vivonics Inc, etc. The leading companies are taking up partnerships, mergers and acquisitions, and joint ventures in order to boost the inorganic growth of the industry.

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In Situ Hybridization (ISH) Market Strategy Framework and Key Companies Analysis by 2013-2024

Global In Situ Hybridization (ISH) Market is expected to reach USD 1.84 billion by 2025. In Situ Hybridization (ISH) is a type of hybridization a method that permits for specific localization of an exact segment of nucleic acid inside a histologic section. That means it involves the use of labeled RNA probes or labeled DNA probes to detect complementary DNA or RNA targets in cytologic preparations or tissue sections. Synthetic oligonucleotides (PNA, LNA), Double-stranded DNA (dsDNA) probes, RNA probes (riboprobes), and Single-stranded DNA (ssDNA) probes are the majorly used ISH probes.

It can be labeled using two major techniques like Non-radioactive labels and radioactive isotopes. A labeled RNA or DNA probe can be used to hybridize to a known target DNA or mRNA sequence within a sample. This labeled RNA or DNA probe can then be detected by using an antibody to detect the label on the probe. The In Situ Hybridization (ISH) industry is estimated to grow at a significant CAGR of 7.3% over the future period as the scope and its applications are rising enormously across the globe. In Situ Hybridization (ISH) Market is segmented based on product type, technology, probe type, application, end use, and region.

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Services, instruments, software, and kits & probes are the product types that could be explored in In Situ Hybridization (ISH) in the forecast period. The instruments sector accounted for the largest market share of In Situ Hybridization (ISH) industry and is estimated to continue its dominance in the upcoming years. This may be because of high demand from research laboratories and diagnostic centers. Also, these instruments are easy to handle, cost-efficient, and portable these factors may lead the sector in coming years. However, kits & probes sector is estimated to grow at highest CAGR in the coming years.

The enhanced technology used in In Situ Hybridization (ISH) is Chromogenic In Situ Hybridization (CISH) and Fluorescent In Situ Hybridization (FISH) that could be explored in the future period. RNA probe and DNA probe are the two main types of probes that could be explored in In Situ Hybridization (ISH) in the foremost period. The DNA probes sector is estimated to account largest revenue shares of In Situ Hybridization (ISH) in the coming years. Whereas, RNA sector is estimated to grow at highest CAGR in the coming years.

The market may be categorized based on applications like infectious diseases, cancer, developmental biology, cytogenetics, and others that could be explored in the future period. Cancer sector accounted for the largest market share of In Situ Hybridization (ISH) and is estimated to grow at highest CAGR in the coming years. The reason could be growing occurrence of cancer and rising research in this sector. However, cytogenetics sector is estimated to grow at fastest pace in the coming years.

End users like academic institutes, research & diagnostic laboratories, contract research organizations (CROs), and others could be explored in In Situ Hybridization (ISH) Market in the forecast period. The research & diagnostic laboratories sector accounted for the largest market share of In Situ Hybridization (ISH) and is estimated to lead the overall market in the coming years. This may be because of growing applications of molecular cytogenetics in diagnostics, rising use of enhanced technology in genomics and molecular cytology, and rising initiative in cell research. However, CROs segment is estimated to grow at fastest pace in the coming years.

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Globally, North America accounted for the largest market share of In Situ Hybridization (ISH) and is estimated to lead the overall market in the upcoming years. The reason behind the growth of overall market could be government involvement for development of novel diagnostic tools, availability of research funds, and developed research centers. The United States is a major consumer of In Situ Hybridization (ISH) in this region.

Instead, Europe and the Asia Pacific are also estimated to have a positive influence on the future growth. Europe is the second largest region with significant market share. However, Asia Pacific is estimated to grow at fastest pace with the highest CAGR in the foremost period. The aspects that may be ascribed to the growth comprise, growing awareness regarding advantages of In Situ Hybridization (ISH) technology in diagnostics and government initiative in R&D investments in the field of molecular biology. The developing countries like India and China are the major consumers of In Situ Hybridization (ISH) industry in the region.

The key players of In Situ Hybridization (ISH) Market are Oxford Gene Technology, Thermo Fisher Scientific, Advanced Cell Diagnostics, Inc., Leica BiosystemsNussloch GmbH, NeoGenomics Laboratories, Inc., BIOVIEW, Bio-Rad Laboratories, Inc., Agilent Technologies, PerkinElmer, Inc., and Merck KGaA. These players are concentrating on inorganic growth to sustain themselves amongst fierce competition. As such, mergers, acquisitions, and joint ventures are the need of the hour.

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Protein Extracts from Single Cell Protein and Other Conventional Sources Market Latest Trends and Future Growth Study by 2025

Global Protein Extracts from Single Cell Protein and the Other Conventional Sources Market is expected to reach USD 26.3 Billion by 2025. Protein Extracts from Single Cell Protein and Other Conventional Sources is used to meet the protein need of raising population. The single cell protein (SCP) is termed as a dried microbial cell or total protein extracted from pure microbial cell culture like fungi, algae, bacteria, and yeast specifically grown on agricultural waste and may be used as food supplement to animals and humans. The production of single cell protein can be done using waste materials like corncobs, wood shavings, sawdust, and others. The protein extracts market is expected to grow at a significant CAGR of 8.4% in the forecast period.

High demand for SCP proteins as it has low fat content and contains about 43 to 85% of protein, growing use of enhanced techniques, high demand for nutritious products, and rising population are documented as major factors of Protein Extracts from Single Cell Protein and Other Conventional Sources Market that are estimated to enhance the growth in the years to come. Protein Extracts from Single Cell Protein and Other Conventional Sources Market is segmented based on sources, applications, and region.

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Fungi, bacteria, algae, yeast, and other sources could be explored in Protein Extracts from Single Cell Protein and Other Conventional Sources in the forecast period. Plant based protein extracts accounted for the largest market share of Protein Extracts from Single Cell Protein and Other Conventional Sources and is estimated to lead the market in the upcoming years.

The Protein Extracts from Single Cell Protein and the Other Conventional Sources market may be categorized based on applications like agriculture & fertilizers, biotechnology, animal feed, and others. The animal feed is sub-segregated into animal feed by animal type and animal feed by grades. Animal feed by animal type includes pet animals, livestock, and fish feed. On the other hand, animal feed by grade includes hydrolysates, concentrates, and isolates. Agriculture protein extracts and animal feed protein extracts accounted for the largest market share of overall market and is estimated to remain dominant in the forecast period. This may be because of high demand for proteins from this section.

Globally, North America accounted for the largest market share of Protein Extracts from Single Cell Protein and Other Conventional Sources in 2016 and is estimated to lead the overall market in the coming years. The reason behind the overall Protein Extracts from Single Cell Protein and the Other Conventional Sources market growth could be, rising use of enhanced biotechnological techniques and presence of key manufacturers in the region. The United States is a major consumer of Protein Extracts from Single Cell Protein and Other Conventional Sources in this region. This may be because, rising research regarding use of microbes as a substitute nutrient source.

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Instead, Europe and the Asia Pacific are also estimated to have a positive influence on the future growth. Europe is the second largest region with significant market share. However, Asia Pacific is estimated to grow at fastest pace with the highest CAGR in the foremost period. The aspects that may be ascribed to the growth comprise developing research centers in emerging countries. Moreover, the developing countries like India and China are the major consumers of Protein Extracts from Single Cell Protein and Other Conventional Sources in this region.

The key players of Protein Extracts from Single Cell Protein and Other Conventional Sources Industry are Marlow Foods Limited, Nutreco, Lallemand Inc., AgriProtein Holdings, BlueBio Tech Int. GmbH, ZEN-NOH, and KnipBio. These players are concentrating on inorganic growth to sustain themselves amongst fierce competition. As such, mergers, acquisitions, and joint ventures are the need of the hour.

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Molecular Cytogenetics Market Size, Status, Top Players, Trends and Forecast to 2025

The global Molecular Cytogenetics Market is estimated to develop at a substantial CAGR for the duration of the prediction period. With reference to the latest study report by the Grand View research Inc., the global Molecular Cytogenetics market is likely to extend USD 3.8 billion by the completion of the prediction period. Plotting of humanoid genome combined with incessant technical progressions in cytogenetic methods, has allowed investigators to increase understanding into the sickness producing mechanism at a genomic along with cellular level. Progress in molecular knowledge has assisted in linking the gap amongst molecular biology and cytogenetics. It was not conceivable by means of conservative cytogenetic methods.

The division of the Molecular Cytogenetics industry on the source of Type of Technology could span Karyotyping [Virtual Karyotyping, Spectral Karyotyping], Fluorescence in Situ Hybridization [FISH], Immunohistochemistry, Comparative Genomic Hybridization [Standard comparative genomic hybridization, Array-based comparative genomic hybridization], and Other Technology.

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The division of the international market of Molecular Cytogenetics on the source of Type of Product could span Software & Services, Instruments, Consumables. The division of the global Molecular Cytogenetics market on the source of Type of End Use could span Pharmaceutical and Biotechnology Companies, Hospitals & Pathology Laboratories, Academic Research Institutes, Clinical & Research Laboratories, and Other End Uses.

The subdivision of clinical & research laboratories had controlled the market in 2016. This is mainly owing to increasing application of cytogenetic methods in clinical analysis. Continuing research relating to pathways underlying numerous chromosomal sicknesses has permitted this subdivision to achieve the biggest stake. The division of the international market of Molecular Cytogenetics on the source of Type of Application could span Personalized Medicine, Genetic Disorders, Oncology and Other Applications.

The division of the international market of Molecular Cytogenetics on the source of Area with respect to Trades in terms of intake, Profits, Market stake and Development percentage of Molecular Cytogenetics could span North America, Europe, Asia Pacific, Latin America and Middle East and Africa. By the source of geography, North America was responsible for the biggest stake in 2016 mostly because of the existence of important native entities, for example Agilent Technologies, Inc. Furthermore, existence of actual governing background for the directive of genetic tests has considerably boosted the provincial market.

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Asia Pacific is likely to appear such as the speedily developing local market for the duration of the prediction. Incessant progress in GDP of nations like India and China is expected to improve the purchasing capacity of customers and motivate the local development. Continuing works and interferences in Asia Pacific relating to present tendencies, progresses in human genetics & sickness administration are motivating the market in Asia. These workspaces are intended at refining alertness regarding the importance of progressive diagnostics and treatments between the people.

The statement revises Trades in terms of intake of Molecular Cytogenetics in the international market; particularly in North America, Europe, Asia Pacific, Latin America and Middle East and Africa. It concentrates on the topmost companies operating in these regions. Some of the important companies operating in the Molecular Cytogenetics on the international basis are Diagnostic Cytogenetics, Inc.[DCI], Cytognomix, Applied Spectral Imaging, PerkinElmer Inc., Oxford Gene Technology, Bio-Rad Laboratories, Inc., Biological Industries USA, Inc., Agilent Technologies, Inc., Danaher, Genial Genetics, CytoTest, Quest Diagnostics Incorporated, F. Hoffmann-La Roche Ltd., Illumina, Inc., Abbott, Meta Systems, and BIOVIEW.

Accepting the increasing demand for cytogenetic examination amongthe residents, companies are creating substantial funds to widen their product range. They are likewise engaging in equally advantageous businesses by way of laboratories and research organizations, which consecutively, increases generation of income for these companies. More or less facility suppliers that propose cytogenetic technique centered facilities are South West Thames Regional Genetics Service, Neogenomics, Genesis Laboratories Inc., Virtual Scientific, WI Cell Research Institute, Inc., OHSU School of Medicine-Molecular and Medical Genetics, Weill Cornell Medicine, ARUP Laboratories, Calgary Laboratory Services, UW Cytogenetic Services and UCLA Health - UCLA Pathology and Laboratory Medicines.

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Cancer Stem Cells Market Analysis By Development Trend, Key Players & Investment Feasibility

Global Cancer Stem Cells Market is anticipated to reach USD 1.6 billion by 2025. The market is anticipated to witness a healthy growth rate in the years to come. Cancer stem cells (CSCs) imply immortal and rare cells within a tumor that can both - self-renew and differentiate into several cell types that form the tumor mass. In addition, the growth of Cancer Stem Cells is controlled through numerous signaling pathways, which control the existence and propagation of these cells. Currently, a number of enterprises are proceeding toward exploration of exact targets that can be used to selectively remove cancer stem cells; thereby causing therapeutic benefits to patients suffering from many forms of cancers.

On the other hand, factors that may hamper the market growth include high costs of cancer stem cell therapeutics. The market is anticipated to grow at a significant CAGR of 9.98% in the upcoming period as the scope, product types, and its applications are increasing across the globe.

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Cancer stem cells industry may be explored by mode of action, forms, and geography. The market may be explored by mode of action as Targeted Cancerous Stem Cells (CSCs). By Anti-Cancer Stem Cell Therapeutics the cancer stem cells market could span Pathway Inhibitors (Notch Signaling Pathway, WNT Signaling Pathway, Hedgehog Signaling Pathway, Others), Immuno-evasion & Targeting Tumor Microenvironment, Surface Marker-based, Nanoparticle-based Therapies, and Others). By-Products, the market spans Cell Separation, Cell Culturing, Molecular Analysis, Cell Analysis, and Others)), and by Stem Cell-based Cancer Therapy the cancer stem cells industry spans Allogeneic Stem Cell Transplant and Autologous Stem Cell Transplant.

Cancer stem cells market may be explored by Forms as Liver Cancer, Blood Cancer, Pancreatic Cancer, Colorectal Cancer, Brain Cancer, Bladder Cancer, Lung Cancer, Breast Cancer, and Other Cancer. The Breast cancer segment dominated the market in the cancer stem cells industry in 2016 and is anticipated to maintain its dominance till 2025. Breast cancer accounted forthe highest share in 2016. North America accounted for the major share of the global Cancer Stem Cells market Size Analysis in 2016 and will continue to rule the roost in the forecast period. North America was followed by Asia-Pacific.

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Some of the key players that fuel the growth of the cancer stem cells industry include Bionomics; AbbVie, Inc.; Stemline Therapeutics, Inc.; Merck KGaA; Lonza; BIOTIME, INC, MiltenyiBiotec; MacroGenics, Inc.; Irvine Scientific; Thermo Fisher Scientific, Inc.; OncoMed Pharmaceuticals, Inc.; Sino Biological Inc.; STEMCELL Technologies Inc.; and PromoCell GmbH. The leading companies are entering into partnerships, mergers and acquisitions, and joint ventures in order to boost the inorganic growth of the industry.

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Cell Isolation/Separation Market Share, Trends, Revenue, Volume and Forecast Report 2025

Industry Insights

The global Cell Isolation/ Separation Market size was estimated at USD 3.6 billion in 2016. There has been a recent increase in the use of the cell isolation in the stem cells research and cancer studies by the biotechnology companies and pharmaceuticals. This has triggered immense demand for related products. The cell separation is used for advanced analytical procedures in cancer and stem cells research. This has resulted in high demand for proteins and in turn is expected to support the cell isolation market during the forecast period.

Personalized medicine is customized medical treatment for each individual which facilitates greater outcomes. The cell isolation market procedures can be used for personalized medicine for the early detection of the diseases and to provide proper treatment. The separation of different cell types is a vital step for research, diagnostics, biomedical, and biotechnological applications. Thus, the rising demand for personalized medicine is a major factor augmenting the cell separation products.

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Product Insights

The product segment is fragmented into consumables and instruments. The consumables segment is estimated to account for the largest market share. The increase in investment in research and development activities by the biotech companies has led to a boost in the cell separation products. This has led to a surge in demand of the cell separation consumables adding to the segment growth.

The instruments segment is projected grow at a significant rate due to product development and advancement during the forecast period. This advancement is helpful in the efficient cell separation and diagnostics purposes. The increasing incidence of diseases is responsible for the rise in demand for therapeutics which in turn is adds to the growth of the separation products.

Type Insights

The wide use of the stem cells in various applications like biopharmaceuticals and other research is a major factor for the growth of the cell separation market. Moreover, the rise in R&D procedure for new product development and clinical trials also add to the cell isolation market share. The animal type is expected to show a fair amount of growth in the forecast period.

The growing government focus on the development of the newer drug discovery along with investments from pharmaceuticals has attributed to the growth of the cell separation market. The drug discovery and research require animal cells for the examination of the preliminary toxicity and efficacy of the new molecule. Thus, the increasing government rigidness regarding animal cells and tissue availability are expected to hinder the market growth.

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Technique Insights

There are different techniques including centrifugation, surface maker, and filtration that are used for cell isolation. The centrifugation segment is expected to hold largest market share in 2016. The rise in the application of cell isolation in the research laboratories, biotech institutes, biopharmaceutical companies and cell banks is accelerating the sector growth during the forecast period.

The filtration and surface marker segment is expected to show significant growth rate during the study period. Product development and rising investment in pharmaceutical manufacturing has led to increased share of the segment. The advanced filtration systems are used for research and production by the manufacturers for assuring the better quality of end product.

Application Insights

The biomolecule segment is reported to have the highest revenue share in 2016. The increasing focus on the production of the biopharmaceuticals such as monoclonal antibodies, biosimilars, and proteins add to the segment growth. Moreover, the increasing research investments and government funding has propelled the sector growth.The cancer and stem cells research segment are expected to exhibit rapid growth in the forecast period. The growing investments made by the pharmaceutical companies in stem cells research is a major factor responsible for the growth of the segment. Investments are expected to yield newer products in the research process, ultimately increasing the demand for the novel and efficient techniques used in stem cells research adding to the market growth.

End User Insights

The end users segment is further categorized into research laboratories, institutes, and biotechnology & biopharmaceutical companies. The research laboratories and institutes segment accounted for the largest market share in 2016. This is due to the increased prevalence of the stem cells and cancer research.

The biopharmaceutical & biotechnology companies segment accounted for remarkable revenue share in the market. This is due to an increase in the R&D investment by biologics manufacturers for research activities related to protein therapeutics, monoclonal antibody, and cancer & stem cells research, which is expected to boost the demand for cell isolation products.

Regional Insights

North America accounted for the largest market share in the 2016. Presence of major biotechnology companies and pharmaceutical companies in the region as well as highly developed infrastructure has contributed to the growth of the regional sector. In addition, product advancements and drug discoveries in the region is further anticipated to boost growth.

Several biotechnology and pharmaceutical companies are penetrating the Asia Pacific region owing to high target population base, increasing disposable incomes, cheap labor, and rapidly growing economy. With highly populated countries, offer a large gene pool for more research thus. further helping the cell isolation market in the region. Moreover, there are less stringent regulations along with the availability of the skilled but cheap worker which add to the market growth.

Competitive Insights

Some of the key players in the market are BD Biosciences; Thermo Fisher Scientific, Inc.; Merck KGaA; Beckman Coulter, Inc.; GE Healthcare; STEMCELL Technologies Inc.; Terumo BCT; and Bio-Rad Laboratories, Inc. The increasing merger, acquisition, and collaboration between the companies have profited the cell isolation market growth. For instance, In August 2016, STEMCELL Technologies Inc. and GE Healthcare announced a licensing agreement. According to which STEMCELL Technologies’ T-Cell reagents will be commercialize by GE Healthcare. This reagent can be used for the separation, culture, and activation of T-cells in clinical applications. Moreover, the newer product launch and regional expansion have also attributed to the market growth.

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Mycoplasma Testing Market Competitor Analysis, Investment Plan and Forecast Analysis by 2025

Industry insights

The global Mycoplasma Testing Market was valued at USD 446.9 million in 2016 and is anticipated to witness a lucrative growth over the forecast period. Rising number of pharmaceutical and biopharmaceutical companies, increasing R&D investment, and growing number of drug launches are major attributes that are fuelling the market. Increase in the number of biopharmaceutical and pharmaceutical companies has been seen in the past years. This growth has been attributed by the need for advanced drugs and therapies for the treatment of chronic diseases like cancer, diabetes, cardiovascular diseases and osteoporosis among others.

The research work is supported by the government by funding the pharmaceutical and biotechnology companies in order to facilitate research based activities for the development of new drugs. This may foster the growth of mycoplasma testing market. Rising investment in R&D by dominant players has further resulted in growth of the market. In the year 2016, North America spent 28.4% of its GDP on research and development according to Global R&D Funding Forecast. This signifies significant rise in the spending by various companies for the invention of new and enhanced testing devices and kits.

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With the growing expenditure by the government in the healthcare industry and awareness campaigns have led to the growth of the mycoplasma testing market. Mycoplasma testing is conducted so as to ensure the product is contamination free during each stage of manufacturing process.Mycoplasma contamination is a major cause of concern in research and development activities. Infections caused by M. orale or M. fermentans are strains that frequently are seen in humans are a key source of contamination in laboratory settings.

These contaminations in cell cultures cause morphological changes, altered cell metabolism and chromosomal aberrations causing contamination in the entire cell line. Contamination may also result in serious complications such as pneumonia, genital infections and other respiratory disorders is also seen. Thus, to prevent such contaminations, mycoplasma testing is vital.

Product Insights

Based on the products, the market is segmented into kits, reagents, instruments, and services. Kits & reagents segment holds the largest market share owing to its repetitive purchase. Kits & reagents segment has been studied after further sub-segmentation into- nucleic acid detection kits, elimination kits, PCR assays, stains, and standards & controls. Instruments segment is projected to show a lucrative growth in the forecast period owing to introduction of advanced automated machines for detection of mycoplasma contamination. The results obtained are fast and highly efficient.

Technology Insights

On the basis of technology, PCR segment held the largest share in 2016. PCR helps to detect the mycoplasma using its double stranded DNA. The DNA of the mycoplasma are amplified, and then a dye is used which attaches to the DNA and emits light. This shows the presence of mycoplasma. Microbial culture is expected to show lucrative growth over the forecast period. The increasing number of research activities in academics, research laboratories, pharmaceutical and biopharmaceutical companies is supporting the growth.

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Application Insights

On the basis of application, cell line testing held the largest share in 2016. Cell line testing is generally conducted in the laboratory and is the major source of mycoplasma contamination. This segment is expected to show growth over the forecast period due to increasing application of mycoplasma testing to avoid contamination in the cell culture. End of production cells is projected to show lucrative growth over the forecast period due to the increase in clinical trials for drug discovery and development. The quality control taken in the drug discovery is majorly contributing to the of this segment share.

End-use Insights

On the basis of end use, pharmaceutical and biotechnology companies contributed towards the largest share in 2016. The government’s support along with the huge investment made by these companies in the R&D activities has led to the development new drugs which in turn has contributed to the growth of the market. Contract research organisations are projected to show attractive growth over the forecast period because large number of research activities is conducted by these organisations which are outsourced by the pharmaceutical and biotechnology companies.

Regional Insights

North America dominated the market in 2016 owing to the rising healthcare expenditure made by the US government in R&D activities for the development of new drugs. There is also spending on healthcare infrastructure which contributes to the growth. Asia Pacific region is projected to show a lucrative growth over the forecast period owing to increasing awareness and funding initiatives undertaken by the government for the development of new drugs.

Competitive Insights

Some of the major key players of the market include Charles River Laboratories International, Inc.; Merck KGaA; Lonza Group Ltd.; Thermo Fisher Scientific; PromoCell GmbH; ATCC (American Type Culture Collection); Biological Industries Israel Beit Haemek Ltd.; Bionique Testing Laboratories, Inc.; and InvivoGen.

The leading manufacturers provide an extensive range of advanced testing products through their strong distribution channels across wide geographical locations. The significant strategies causing the growth of these companies include new product development, geographical expansions, and mergers & acquisitions. For example, in November 2015, Merck acquired Sigma-Aldrich Co., one of the major in the industry.

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Biopreservation Market Product Analysis & Regional Analysis From 2014 to 2025

Industry Insights

The global Biopreservation Market size was estimated at $2.61 billion in 2014 and is anticipated to grow at a CAGR of 17.3% during the forecast period. Rapid growth can be attributed to the rise in healthcare expenditure which is expected to boost the market in the forecast period. Moreover, increasing R&D activities by various companies as well as research organizations funded by government initiatives in the form of grant, contacts and various other funding mechanisms have led to development of novel and innovative bio-preservation services, leading to augment the revenue growth. Growing use of bio-preservation are also supported by the rising participation of government or non-government bodies for the development of this field. For example, due to the support of the institutional and government repositories, the storage of bio-specimen has evolved to next level of advanced information from basics of patient’s phenotype, extending to genetics as well as “omics” such as proteomic information.

Product Insights

The key segments included laboratory information management systems (LIMS), media and equipment. In 2014, the equipment segment dominated the market which includes liquid nitrogen, consumables, refrigerators and freezers, having a revenue share of more than 80%. The larger share can be attributed to the high demands pertaining to bio-banks and the extensive use and importance of the aforementioned products in bio-preservation.

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Media segment which includes home brewed and pre-formulated media is projected to witness a healthy growth as a consequence of the increased demands of tissues, cells and other materials in bio banking and advanced products in regenerative medicines. Furthermore, the high share and preference of home brewed media in terms of bio-storage can be attributed to its cost-efficiency and effectiveness in comparison to pre-formulated media.

Application Insights

The major application analyzed in the study comprised of drug discovery, bio-banking and regenerative medicines. Moreover, the further segmentation of bio-banking includes veterinary IVF, human sperm and human eggs. Bio-banking segment held the largest share of 72.5% in 2014. Rising awareness related to preservation of stem cells, use of assisted technology for reproduction in animals and increasing number of sperm and egg banks are anticipated to drive the growth. Additionally, the expected rise in the revenue share of the segment can be attributed to advent of new techniques used for preservation of cells for a longer span of time. Regenerative medicine is considered to be the fastest growing segment owing to the high demand pertaining to efficient and specialized techniques for bio-storage. Moreover, huge amount of investments by non-government or government organizations in the field of regenerative cell therapy research is projected to boost the growth of the overall market.

Cell providers Insights

The segment of cell providers can be analyzed on basis of tumor cells, hESC, iPSC, MSC, CD19+, and CD34+. The largest market share was held by tumor cells in terms of volume in 2014 as a consequence of their wide array of application in treatment, diagnosis and R&D of the most prevalent forms of cancer. However, the fastest growing segment is predicted to be the iPSC segment throughout the forecast period because of their promising application in regenerative medicines owing to their high propagating capacity.

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Regional Insights

Key market in 2014 was the North American having a revenue share of more than 45% owing to the innovative drug developments and therapies pertaining to the biomedical research. Also, continuous rise in the population base with chronic and acute disorders requiring treatment and diagnosis in the region is further drive the revenue generation. Asia Pacific region is expected to show a considerable growth rate over the forecast period owing to the rise in population base suffering from life threatening disorders. Moreover, increasing investments by government in R&D is leading to an urgent need for bio-storage, therefore providing a boost to the regional market.

Market Share Insights

The key players holding a significant share of the biopreservation market include Qiagen, Thermo Fisher Scientific Inc, Panasonic Biomedical, Atlanta Biologicals, LabVantage Solutions Inc., Chart MVE Biomedical, BioLife Solutions Inc., Biomatrica and BioCision. The strategic initiatives by the company including acquisitions, mergers and new product launches are done to maintain and gain a competitive edge. For instance, ATCC and BioCision in May 2013 entered in an agreement to distribute and develop line of CoolProducts having a wide array of applications in wielding procedures and biomaterials storage.

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Biochip Market Growth, Supply Demand and Analysis By Types 2013-2024

Industry Insights

Global Biochips Market size was valued at USD 7.63 billion in 2015. With potential applications of genomics and proteomics in biotech R&D, along with rapid technological innovation and increase in adoption of personalized medicines, it is expected that this market will witness considerable growth in revenue over the forecast period. For biochip technology, in order to enhance its usability, there is an improvement in resolution, preparation procedures and accuracy along with the reduction in the cost of the materials associated with manufacturing the biochips. These factors are expected to further reinforce growth potential. Anticipated commercialization and launch of novel treatments and diagnosis products including non-laboratory and laboratory research is expected to fuel growth over the forecast period.

Current developments aiming to miniaturize biochips even further can be anticipated to increase the additional usage and applicability for genetic sequencing methodologies, such as diabetes genomics. With the rise in usage of the biochip technology, it is anticipated that cost of genome profiling can reduce even further for studies such as protein expression analysis among others. Hence, proteomics and genomics labeling techniques along with other protein profiling techniques are expected to witness a growth in demand.

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Product Type Insights

DNA chips accounted for the largest share of revenue owing to the presence of a considerable number of applications. Cancer treatment/diagnostics has been observed to have major share for the usage of biochips. Other segments contributing for the applications of biochips include genotyping, agricultural biotechnology, genomic studies, single nucleotide polymorphism and gene expression. Biochip technology has the ability for miniaturizing chemical & biological assays and molecular biology which provides a ground for in-depth R&D of molecular biology at a minute level. Furthermore, the ability of miniaturization is expected to improve even more and enhance the efficiency in terms of inputs and cost requirements.

End-use Insights

Lab-on-a-chip, cell and tissue array, protein chips and DNA chips find applications in biotechnology & pharmaceutical companies, research & academic institutes, hospitals & diagnostics and point of care settings which involves end users. Protein biochips and LOACs have found widespread use for single nucleotide polymorphism genotyping, gene expression, in vitro diagnosis, expression profiling, drug discovery, high throughput screening and tissue arrays. The commercialization of the products in the development pipelines of key market participants is also key towards the potential to drive the growth for the market.

Sophisticated robotic tools are needed for scanning and handling samples which are in micro-scale. Furthermore, for efficient data analysis efficient bioinformatics system is required. Therefore, this will increase the need for specific techniques and system which is expected to increase the demand for biochips used in sophisticated machines. This will consequently increase the price of the biochips and widen the offered product range in the market.

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Regional Insights

North-America accounted for the largest revenue share owing to the presence of government policies motivating personalized care for the patients and availability of proteomics and genetic profiling infrastructure across the country, especially in the U.S. There has also been a rise in the usage of NGS (Next Generation Sequencing) for molecular treatment and clinical diagnosis coupled with microfluidic techniques that add to the large market share.

The Asia Pacific region is expected to grow at the fastest rate during the forecasted period. Reasons contributing towards the fastest growth in the market are – increase spending by the government in order to improve healthcare and R&D infrastructure in the areas of proteomics, genomics and NGS (next generation sequencing). There has also been growing awareness in the growth market for early and effective diagnosis which will further increase the growth in the market.

Competitive Insights

Key players in the development & commercialization of biochips include PerkinElmer, Inc.; Abbott Laboratories; Bio-Rad Laboratories, Inc.; Fluidigm Corporation; Sigma-Aldrich Corporation; Agilent Technologies, Inc.; Thermo Fisher Scientific, Inc. and GE Healthcare. In order to establish themselves in the untapped market, companies are following various strategies including mergers & acquisitions, collaboration, vertical and horizontal integration in regions/countries where they can see potential growth.

For example, PerkinElmer has successfully taken over Vanadis diagnostics which undergoes cell free DNA-based noninvasive prenatal testing (NIPT) on the digital platform. This has extended PerkinElmer’s portfolio. Similar strategies by other companies is expected to influence the market positively which will also bring competitiveness in the market.

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Next Generation Sequencing (NGS) Market Research Report Released with growth, latest trends & forecasts till 2025

The global Next Generation Sequencing Market is anticipated to reach USD 21.4 billion by 2025. NGS market is expected to show a tremendous growth on account of its wide applications in the treatment of cancer. NGS is the process of identifying accurate order of nucleotides within a RNA or a DNA molecule. Advancement of NGS has helped biological and medical discovery and research. It has helped in various applied fields which includes biotechnology, forensic research, virology and medical diagnosis. NGS has made possible sequencing of DNA of various species including the human genome.

Introduction of advanced genetic sequencing and development of advance techniques for whole genomes are the major drivers contributing to the overall market growth. Increasing incidences of cancer and infectious diseases coupled with aging population is expected to fuel the demand for these technologies.

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Further, the overall cost of genome sequencing is expected to reduce drastically on account of rapid development through research and innovation. High capacity genome sequencing has been contributing significantly towards the market growth. NGS has wide applications in the field of exome and genome sequencing. They are widely used in the treatment of infectious disease and cancer. NGS has shown a key presence in pathogen analysis which has been helpful in the treatment of infectious diseases. The need for effective diagnosis for cancer and high growing usage of combinational biomarkers are other factors contributing to the growth of the market in recent years.

NGS has been mostly a topic of research and development in the previous decade. At present they find applications in the field of oncology, prenatal testing, HLA testing, idiopathic diseases, and medical research. Research and development in the field of HLA and prenatal testing have provided new avenues to doctors in gaining insights during organ matching and organ rejection.

The development in the treatment of genetic anomalies and diseases with the help of prenatal genome sequencing has been driving the NGS market. This technology has also helped the pharmaceutical companies in developing essential drugs for the treatment of cancer and infectious diseases. Growing concerns and increasing incidences of cancer is expected to be the major driving factor for the development of NGS.

NGS in the field of organ transplant provides great opportunities over the forecast period. It is important that the characteristics of both the donors and the acceptors match for a successful transplant. NGS helps in studying the immune response to the transplanted organ. Medical tourism development in countries including the U.S, Israel, Singapore and Australia provide bright prospects for overall growth of the market.

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Next generation sequencing market is segmented as target, genome, exon and resequencing. The largest share is held by target sequencing followed by genome sequencing. Development of whole genome sequencing capabilities is expected to show a significant growth over the forecast period. Whole genome technology is relatively new and is gaining popularity with the development of high throughput. This high throughput has helped in reducing complications associated with whole genome sequencing.

NGS includes sample enrichment, DNA tagging, library preparation, sample quality assurance, DNA quantification, data storage, genetic data assembly, analysis and interpretation. With the increase in volume of whole genome sequencing, next generation data analysis is expected to observe a significant growth over the forecast period.

Government regulatory bodies play a vital role in overall development and usage of these technologies. Medical device manufacturers in the U.S. are under the strict vigilance of Food and Drug Administration (FDA). In 2013, FDA approved four next generation gene sequencing devices which is expected to help physicians in taking a broader look at the patient’s genetic makeup. Two of the approved devices is expected to help in detecting DNA changes in the treatment of cystic fibrosis.

North America is expected to observe highest demand in the global industry on account of the well-developed healthcare sector and implementation of advanced research infrastructure. Similarly, Western Europe is expected to show a substantial demand over the forecast period on account of increasing emphasis by the regional government on healthcare facilities coupled with the stringent regulatory framework. Asia Pacific and the Middle East are expected to observe significant growth on account of the increasing government initiatives to establish proper healthcare infrastructure in developing economies including China, India, Japan and UAE.

The NGS market is dominated by few players with the help of proprietary platforms. The key industry players include Life Sciences (Roche), Thermo Fischer Scientific, Illumina and Pacific Biosciences. Other major players operating in the market include Partek Inc., Genomatix Software GmbH, Macrogen Inc., Life Technologies Corp, Perkin Elmer inc., Oxford Nanopore Technologies Ltd., Knome Inc, Agilent Technologies Inc., Biomatters Ltd., CLC Bio (Qiagen), Pacific Biosciences, BGI (Beijing Genomics Institute), DNASTAR Inc, GATC Biotech and Qiagen N.V.

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Orthobiologics Market Size, Top Key Players, Drivers and Trends by Forecast to 2025

The global Orthobiologics Market size was valued at USD 5.0 Billion in 2015 and is anticipated to reach USD 10.2 billion by 2025, with a CAGR of 7.5%. Orthobiologics are elements which the orthopedic surgeons use to heal the wounds more quickly. They are utilized for the healing of injured muscles, ligaments, tendons, and broken bones. They are made up of substances found in the human body itself. These elements found popularity owing to factor such as faster healing, quick recovery, and a decrease in the number of hospital visits. The orthobiologics market provides a huge number of opportunities for growth to its shareholders.

The global orthobiologics market is poised for growth owing to the increased levels of geriatric population, technological advancements, changing lifestyles and problems related to the musculoskeletal system. The increasing trends of musculoskeletal procedures are seen to be the biggest driver for the market. Establishing strategic partnerships for the purpose of marketing is also expected to boost the demand for the global orthobiologics market. Several merchants are forming strategic partnerships to diversify their businesses, grow their overall market share and spread out their product offerings. These type of strategic alliances help the organizations to align their technologies with one another’s inventive medical device range.

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A growth in the global orthobiologics market is projected on account of the requirement for safer, more effective and modern orthopedic biologic treatment. The rise in the number of obesity and arthritis cases also fuels the demand for orthobiologics treatment. The bone graft procedure accounted to be the largest segment in the global orthobiologics market.

The shifting preference to biological implants from mechanical implants is accelerating the growth of this market. Another important trend that is estimated to enhance the growth of the market over next eight years is the increase in funds to improve orthobiologics. Factors such as growing advances in technology, the prevalence of a huge number of chronic and unidentified diseases, initiatives by the government and rise in life expectation may favorably impact the market growth. Along with this, the rising incidences of injuries by sports & road accidents and growing awareness among athletes are also driving the demand for the market.

However, lack of clear reimbursement procedures and rigorous rules may create major hindrances for the orthobiologics demand in the market. The improvements in developing alternatives for pharmaceuticals, for making medical treatments more preventive than curative along with the country’s policy for decreasing the deficit in the budget is expected to negatively impact the global orthobiologics market. Furthermore, high costs for the procedure, lack of reliable clinical trial data and strict regulations for the approval of orthobiologics products may pose challenges to the market growth over the forecast period.

The global orthobiologics market has been segmented based on its applications and product types. On the basis of application, the market been classified into spinal surgery, joint replacement & reconstruction, and trauma surgery. On the basis of product types, the market has been segmented into bone graft substitutes, bone growth stimulators, and viscosupplements. The bone graft substitutes have further been segmented into demoralized bone matrix (DBM), bone morph genic proteins (BMP), bone allografts, and bone autographs. Additionally, viscosupplements has also been further segmented into single injection viscosupplements, 3-injection viscosupplements, and 5-injection viscosupplements.

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Over the past few years, the viscosupplements segments held the largest market share for orthobiologics on account of huge demand for knee treatment procedures. It is a very effective pain killer. Viscosupplements are intra-articular injections made of hyaluronic acid which helps in the treatment of osteoarthritis.

North America held the majority of the global orthobiologics market in the recent past. The high demand in the market was sustained by increased prevalence of arthritis and obesity in the region, rising demand for the treatment of various diseases such as osteoarthritis and spinal injuries. However, over the next eight years, Asia-Pacific is projected to witness the highest rate of growth for orthobiologics market. This growth will be majorly driven by the Indian and Chinese market on account of a huge number of untapped patient population, economical cost, and medical tourism.

The major industry players operating in the global orthobiologics market include Stryker Corporation, Synthes, Inc., Biomet, Inc., DJO Global, Zimmer Holding, Inc., Medtronic, Inc., and Smith & Nephew, Bacterin International, Inc., DePuySynthes, Inc., Globus Medical, Inc., and Integra LifeSciences Corporation.

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